Asymmetric and symmetric encryption, different algorithms (AES/DES), block/stream ciphers, operation modes - all of these terms are difficult enough on their own, put aside their specific implementation in Your Programming Environment of Choice. You usually need strong math skills to get through all the tiny details that matter in cryptography. To make things worse, cryptanalysis attacks are constantly improving, so you also need to stay current.
Thankfully, you don't need all that much to simply use it. After all, you're not inventing a new home-brew encryption algorithm (if you do - stop immediately!), so all you need to do is RTFM.
But that enough is difficult, because the web is filled with code examples that are simply wrong. It's always a good idea to do some code review for a cryptography related parts of your project. As an example, we'll look into Android Remote Notifier project - it had a few interesting vulnerabilities which significantly weakened its cipher strength. Author took my comments into consideration and fixed the issues, so consider this a "responsible disclosure" ;).